Creutzfeldt-Jakob Disease: What to know Creutzfeldt-Jakob Disease (CJD) is a rare, rapidly progressive brain disorder caused by abnormal prion proteins that damage brain cells. Individuals with CJD may experience memory loss, confusion, speech difficulties, visual disturbances, and impaired coordination. Due to the rapid progression of the disease, early medical evaluation and supportive care are essential for symptom management and patient comfort. Although no cure currently exists, ongoing research aims to improve diagnostic and therapeutic approaches for CJD. Experts regularly share new findings and discuss advances in brain health at the Dementia World Conference (DWC), fostering collaboration to enhance care and understanding. They work together to improve care and understanding.